Plague Inc: Evolved – Cure the Bioweapon With a Vaccine [Normal Difficulty]

[Introduction]

Welcome to my guide to cure the bioweapon with a vaccine on normal difficulty. This guide refers to the game version “1.18.3.2 steam”. Please note, that this guide does not ensure a 100% guaranteed win cause of some luck based mechanics within the game. You may need to restart the run several times to get the proper requirements for a successful attempt, reload your save games multiple times and/or start a completely new run, although you reached phase 5 of this guide. This can be very frustration but don’t give up. However, you can also win the game flawless on the first try (if you are lucky) with this guide. 🙂 
 
In general, events can appear which increases or decreases the difficulty to win the game. If one of the negative events occurs (especially early in the game) then load the last checkpoint. For example: The infection rate of the weapon increases or more effort is necessary to cure the disease etc. 
 
Also restart, if the bioweapon spreads to a country which is not located in Africa until you reached at least step 4. After step 5, don’t care about the spreading anymore since your cure progress should be unstoppable. 
 
This guide includes several screenshots to show you some specific moments. Please note, that these screenshots are taken during different runs so that some do not necessarily refer to the progress of this guide. 
 
 
 

[Advisors]

Choose the following advisors: 

• Economic Forecaster 
• Strategic Fundraiser 
• Disaster Manager 
• Celebrity Scientist 
• Forensic Epidemiologist

[Phase 1]: Getting Started

Start in Saudi Arabia. 
 
[Buy]: 

• Investigate Outbreaks [Operation] 
• Government Partnerships [Operation] 
• Deploy Field Operatives [Operation]

 
[Note]: 
Explore the continent Africa with your team. The disease have to start in a country located at the African continent. Whereby the origin country of the bioweapon highly influences the probability that the disease spreads to a non-African country. Hence, I recommend a country without any sea or airports, but this is not absolutely required because I was able to win the game multiple times while the disease started in West Africa. If the weapon starts somewhere else restart the game since your run is already lost. 
 
[Checkpoint 1]: After you got a fancy country save the game. 
 
 
 
 
 

[Phase 2]: Shut Them Down

[Attention]: 
Continuously send your team to African countries which are not already spotted by one of your teams to get their red bubbles after they were infected by the bioweapon. This step is very important since you need the resource points to quickly buy the next measures and discover where exactly the disease spread since the bioweapon have to stay in Africa! Also check at the control (stats) page, if the origin country is located in Africa to ensure that the weapon don’t came from somewhere else. 
 
[Attention]: Buy the following quarantine measures as fast as you can! 
[Buy]: Shut down the air/sea/land borders for Africa in this order. [Quarantine] 
 
[Note]: After Africa is fully explored, send your team to countries around Africa so that you get noticed if the disease spreads to one of them. Remember to reload the last checkpoint if the bioweapon leaved the continent. 
 
[Attention]: Continue with the following steps while sending your team around. 
 
[Save]: 7 Resource Points 
[Buy]: Furlough Schemes (Non Compliance I) [Operation] 
 
[Save]: 8 Resource Points 
[Attention]: Buy the following two operations simultaneously! 
[Buy] Targeted Economic Aid [Operation] & Debt Relief [Operation] 
 
[Checkpoint 2]: Save the game. 
 
[Note]: 
Now the game will give some money (your resource points) automatically to countries which are shut down. So don’t wonder if some of your Resource Points are withdrawn from time to time. Hence, I recommend to slowing down the game speed so that you are able to grab the points you need before they are gone. 
 
 
 

[Phase 3]: Start With The Research

[Note]: Wait, until the analysis of the disease completed. 
 
[Save]: 10 Resource Points 
[Buy]: Vaccine Research [Operation] 
 
[Attention]: 
Send your team to the origin country of the disease (you can find the information at the control (stats) page) and leave your team there for the rest of the game hence they will generate a lot of important research points which speeds up the developing of the cure. 
 
[Save]: 7 Resource Points 
[Buy]: Field Research [Operation] 
 
[Note]: 
Now you have a chance to find patient zero at the origin country so that the vaccine development increases enormously. Yeah! But this event is totally random and not necessary to the win the game, but it helps a lot! 
 
 
 
 
 
[Save]: 5 Resource Points 
[Buy]: Vaccine Manufacturing [Operation] 
 
[Save]: 9 Resource Points 
[Buy]: Accelerated Research [Operation] 
 
[Save]: 8 Resource Points 
[Buy]: Accelerated Manufacturing [Operation] 
 
[Checkpoint 3]: Save the game. 
 
 
 

[Phase 4]: Push The Vaccine Research Progress

[Save]: 7 Resource Points 
[Buy]: Declare Armageddon [Operation] 
 
[Note]: Your Research Progress should be around 13 % 
 
[Save]: 3 Resource Points 
[Buy]: Clinical Treatments[Response] 
 
[Save]: 7 Resource Points 
[Buy]: Ventilators [Response] 
 
[Save]: 9 Resource Points 
[Buy]: Steroid Modification [Response] 
 
[Attention]: Wait until you have 40 % Research Progress. 
[Note]: At this point, it doesn’t matter anymore if the disease spreads outside of Africa. 
 
[Checkpoint 4]: Save the game 
 
[Buy]: Bypass Safety Measures [Operation] 
 
[Checkpoint 5]: If successful then save the game else reload [Checkpoint 4] 
 
 
 
 
 

[Phase 5]: The Final Steps

[Note]: 
If you got the patient zero event before, better buy Global Manufacturing Treaty for 28 resource points and skip the 3 steps below since your cure research progress is far enough at this moment. 
 
[Save]: 21 Resource Points 
[Buy]: Global Research Treaty [Operation] 
 
[Save]: 11 Resource Points 
[Buy]: Interferon Treatment [Response] 
 
[Save]: 17 Resource Points 
[Buy]: Improve Supply Chains [Response] 
 
[Attention]: 
As I mentioned before, you need a little bit of luck to win the game. At this point, you may have to buy all authority measures! If your authority collapsed nevertheless, I recommend reloading one of the checkpoints or starting a completely new run. However, I got runs where I didn’t really need to buy any of them. 
 
[Note]: Now wait until the vaccine is developed and delivered to the world. 
 
 
 
The screenshot shows the results from one of my runs by using this guide and the patient zero event. 
 
 
 

[Conclusion]

Congratulations you have cured the bioweapon! 
 
So, I hope this guide worked for you or at least give you an idea how a successful strategy looks like. If this guide helped you, feel free to give a rating or a thumb up. Thank you 🙂 
 

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