Here are the most useful skills and abilities in my opinion. You can get up to 16 slots if you have dlc’s.
 
 

1. Survival Instict

Survival Instict will boost Geralt’s health pool.
 
 
 

2. Crippling Strike

Crippling Strike will do damage over time from a bleed status affliction that is going to chip away at enemy health while Geralt continuously attacks.
 
 
 

3. Deadly Precision

Deadly Precision makes it so every adrenaline point adds a one percent chance of killing an enemy instantly.
 
 
 

4. Undying

If Geralt’s health reaches zero then this skill automatically will bring him back to life by spending adrenaline points.
 
 
 

5. Active Shield

Active Shield blocks attacks while draining Geralt’s stamina.
 
 
 

6. Resolve

Resolve will lessen the number of points lost when taking damage.
 
 
 

7. Melt Armor

Melt Armor will make Igni permanently weaken the armor of enemies.
 
 
 

8. Delusion

Delusion allows player to avoid unpleasant situations which would result in unnecessary bloodshed or loss of money.
 
 
 

9. Fleet-Footed

Fleet-Footed reduces damage to hits received while dodging.
 
 
 

10. Whirl

Geralt spins while dealing damage to anyone near him in a wide circle.
 
 
 

11. Strong Back

Strong Back increases maximum inventory weight.
 
 
 

12. Focus

Focus increases weapon and sign damage.
 
 
 

13. Muscle Memory

Muscle Memory increases fast attack damage.
 
 
 

14. Strength Training

Strength Training increases strong attack damage.
 
 
 

15. Sun and Stars

Sun and Stars regenerates Geralt’s health when he is not in combat during the daytime. At night, stamina regenerates by an additional 1 points per second during combat.
 
 
 

16. Gourmet (Blood and Wine exclusive)

Gourmet makes eating food regenerate Geralt’s vitality for 20 real-life minutes.
 
 

 
 
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