The Binding of Isaac: Rebirth – Easy Unlocks – Tainted Cain Strategy

The Binding of Isaac: Rebirth – Easy Unlocks – Tainted Cain Strategy 1 - steamlists.com
The Binding of Isaac: Rebirth – Easy Unlocks – Tainted Cain Strategy 1 - steamlists.com
Tired of wanting to become back your money?
This guide will help you beat trash Issac using the most broken character!

 
 

Introduction

 
Hello… 
 
I suppose you are currently feeling like this Twitter user, the man who took out his rage on an innocent game developer over his/her lack of skill… 
 
The Binding of Isaac: Rebirth - Easy Unlocks - Tainted Cain (Cillith) Strategy 
 
This strategy will allow you to become Lilith as Tainted Cain, adopting her love for familiars and using said familiars to form an army of unstoppable anguish, hence Cillith (Lilith + Cain + Kill = Cillith) 
 
 

Contents

 

Early Game

 
Crafting 3 Freezer Babies, 1 Tractor Beam, and a whole lot of pain! 
 

Mid-Game

 
Crafting more familiars, building your army to slay whatever enters your path! 
 

Late-Game

 
Do what you need to do basically, a useless section of encouragement! 
 

Switching to Other Characters

 
Utilising The Clicker, also telling you how not to break the game and get stuck as Tainted Forgotten 
 

Useful Synergies

 
Some great trinkets and items to aid your army further! 
 

Conclusion

 
Thanks for reading! 
 
 

Early Game

 
Step 1: Start The Run 
Okay, first off you need to start your run as Tainted Cain. 
 
Step 2: Conjoined 
Okay, this is the hardest part. You are going to need 3 familiars to get the Conjoined Transformation
 
The easiest and strongest familiar to craft is the Freezer Baby, costing only: 
1 red heart, 5 pennies, 2 bombs 
 
Step 3: Tractor Beam 
Once you are Conjoined, craft yourself a Tractor Beam
6 pennies, 2 keys 
 
Step 4: BFFs! (OPTIONAL) 
This is entirely optional but highly recommended, craft BFFs!
1 soul heart, 2 pennies, 5 bombs OR 2 red hearts, 1 penny, 1 nickel, 2 keys, 2 bombs 
 
Step 5: Birthright (OPTIONAL) 
Another optional but highly recommended item is Birthright, as it increases the amount of drops from item pedestals, i.e. more material to craft with! 
2 red hearts, 2 soul hearts, 3 pennies, 1 bomb OR 3 pennies, 4 bombs, 1 pill 
 
________________________________________________________________ 
 
That’s your DPS set up for now! You can steamroll early-game bosses efficiently with the familiars and triple shot you just gained, alongside your supportive frozen friends! 
 
 

Mid-Game

 
As you go further into mid-game (i.e. Depths), you’re going to want to build your army further, crafting as many cheap familiars as possible (or more expensive one’s, depending on your luck). 
 
This is where the guide is flexible, you can either build up the army or focus on building up your tear rate, damage or range! 
 
_______________________________________________________________ 
 
Cheap Familiars 
These familiars are the cheapest, easiest to obtain! 
 
Little Steven1 red heart, 1 soul heart, 1 penny, 1 key, 4 bombs 
 
Brother Bobby1 soul heart, 4 pennies, 1 key, 2 bombs 
 
Robo-Baby4 red hearts, 2 pennies, 2 keys 
 
Rainbow Baby7 pennies, 1 nickel 
 
______________________________________________________________ 
 
Useful Familiars 
These familiars are going to help carry your run, however they are not the cheapest so if you have crafted Birthright, you may be lucky enough to get these! 
 
Incubus1 red heart, 4 soul hearts, 1 black heart, 1 key, 1 rune/soul 
 
Guardian Angel3 red hearts, 1 eternal heart, 1 penny, 2 keys, 1 bomb 
 
Lil’ Brimstone4 soul hearts, 2 pennies, 1 nickel, 1 bomb 
 
Rotten Baby1 soul heart, 1 penny, 3 nickels, 3 bombs 
 
 

Late-Game

 
Okay, so you reached end-game, you’re probably vibing in Cathedral / Sheol / Corpse, or you’re moving your way back up to the beast. This is where you can either do the dirty Bait & Switch or go beat the bosses as Tainted Cain. 
 
_______________________________________________________________ 
 
Pretty much keep going how you are, focus on your build, or just bulk up and let the army of familiars do the work! This is entirely your call now! 
 
 

Switching to Other Characters

 
The Bait & Switch 
Okay so you are going for unlocks for other characters, you are going to want to craft some things before you go for The Clicker
 
Step 1: The Battery 
You are firstly going to need The Battery, the reason being is you need two, full charges on The Clicker so you don’t get stuck as Tainted Forgotten. 
 
The Battery is cheap so don’t stress: 
3 red hearts, 1 soul heart, 4 pennies OR 4 pennies, 1 nickel, 1 key, 2 bombs 
 
Step 2: Battery Pack (OPTIONAL) 
Okay, now you have 2 charges, it’s time to get some batteries spawning, you can do this by crafting the Battery Pack
6 red hearts, 2 pennies OR 4 red hearts, 3 pennies, 2 keys 
 
Step 3: The Clicker 
Here’s how you switch to another character, although you will lose 1 item per transformation, so maybe craft a bunch of Breakfastor other trash items so you can keep the good stuff! 
 
The Clickeris crafted cheaply and easily, and using the batteries you can get to your desired character easily! 
 
The Clicker: 
3 red hearts, 1 penny, 2 keys, 1 bomb, 1 pill OR 2 red hearts, 2 pennies, 2 nickel;s, 1 key, 1 bomb 
 
_______________________________________________________________ 
 
It’s useful to note that using the clicker can actually be really helpful, for example Tainted Lazarus will not switch to his Dead form, meaning you do not have to deal with that BS! 
 
All in all, EZ win! 
 
 

Useful Synergies

 
Here’s a few useful pick-ups for your journey! 
 
Baby Bender Trinket – Familiars get homing shots 
 
Friendship Neckless Trinket – Familiars circle you 
 
Box of Friends – Duplicates all familiars for the room (CANNOT USE WITH CLICKER
2 red hearts, 1 soul heart, 1 penny, 1 key, 2 bombs, 1 card 
 
Extension Cord Trinket – Electricity connects all familiars 
 
Forgotten Lullaby Trinket – Buffs all familiar tear rate 
 
 

Conclusion

 
Thank you for reading! 
 
This is my first ever guide, I may update with extra (disgusting) ideas or add some of your suggestions (with credit of course!) 
 
Comment what other synergies, tips or tricks you have and I hope this strategy serves you well! 
 

Written by Clarky01

This is all about The Binding of Isaac: Rebirth – Easy Unlocks – Tainted Cain (Cillith) Strategy; I hope you enjoy reading the Guide! If you feel like we should add more information or we forget/mistake, please let us know via commenting below, and thanks! See you soon!
 
 
 
 


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