The Binding of Isaac: Rebirth – Card Reading in Repentance

0 – The Fool?

0 – The Fool? – Drops all hearts and pickups on the floor, leaving Isaac at half a heart.
Unlock method – Defeat Ultra Greedier as Tainted Lost

I – The Magician?

I – The Magician? – Grants a repelling blue aura for one minute, like The Soul but stronger and with a wider area of effect.
Unlock method – Ultra Greedier as Tainted Judas

II – The High Priestess?

II – The High Priestess? – Mom’s leg starts stomping down repeatedly for one minute, like holding Broken Shovel.
Unlock method – Defeat Ultra Greedier as Tainted Lilith

III – The Empress?

Does not stack.
III – The Empress? – Grants 2 temporary red heart containers and +1.35 tears for one minute, along with Magdalene’s hairstyle.
Unlock method – Defeat Ultra Greedier as Tainted Eve

IV – The Emperor?

IV – The Emperor? – Teleports Isaac into an extra Boss Room. The boss will drop a reward, but the room has no trapdoor and can be returned to only with another card.
Unlock method – Defeat Ultra Greedier as Tainted ???

V – The Hierophant?

V – The Hierophant? – Spawns 2 Bone Hearts.
Unlock method – Defeat Ultra Greedier as Tainted Bethany

VI – The Lovers?

VI – The Lovers? – Spawns a random item from the current room’s item pool. Turns 1 red heart container or 2 soul hearts into a broken heart, potentially fatally.
Unlock method – Defeat Ultra Greedier as Tainted Magdalene

VII – The Chariot?

VII – The Chariot? – Isaac becomes an invincible, immobile statue with extreme fire rate for 10 seconds. Sometimes the statue looks like Edith. Edith is the secret character from mod Antibirth.
Unlock method – Complete Hot Potato (challenge #42)

VIII – Justice?

VIII – Justice? – Spawns 2 to 4 Golden Chests.
Unlock method – Complete Cantripped (challenge #43)

IX – The Hermit?

IX – The Hermit? – “Sells” items and pickups in the room for their usual shop price, spawning a matching amount of coins. Does not affect grab bags. If there is nothing to sell, spawns a penny.
Unlock method – Complete Red Redemption (challenge #44)

X – Wheel of Fortune?

X – Wheel of Fortune? – Invokes a random dice room effect.
Unlock method – Ultra Greedier as Tainted Cain

XI – Strength?

XI – Strength? – All enemies in the room are weakened, becoming slow and take double damage.
Unlock method – Ultra Greedier as Tainted Samson

XII – The Hanged Man?

XII – The Hanged Man? – Isaac turns visually into Keeper for 30 seconds, with a triple shot, no damage bonus and -0.1 speed. Killed enemies drop random coins.
Unlock method – Defeat Ultra Greedier as Tainted Keeper

XIII – Death?

XIII – Death? – Invokes Book of the Dead Book of the Dead effect.
Unlock method – Defeat Ultra Greedier as Tainted Forgotten

XIV – Temperance?

XIV – Temperance? – Forces Isaac to eat 5 random pills in quick succession.
Unlock method – Complete DELETE THIS (challenge #45)

XV – The Devil?

XV – The Devil? – Invokes The Bible and grants Seraphim familiar and flight for 30 seconds.
Unlock method – Defeat Ultra Greedier as Tainted Azazel

XVI – The Tower?

XVI – The Tower? – Spawns 6 clusters of random rocks and other obstacles. The pathways between exits can’t be blocked.
Unlock method – Defeat Ultra Greedier as Tainted Apollyon

XVII – The Stars?

XVII – The Stars? – Removes Isaac’s oldest passive item and spawns 2 random items from the current room’s item pool.
Unlock method – Ultra Greedier as Tainted Isaac

XVIII – The Moon?

XVIII – The Moon? – Teleports the player to the Ultra Secret Room. The pathway back to the normal rooms will be made of red rooms.
Unlock method – Defeat Ultra Greedier as Tainted Jacob

XIX – The Sun?

XIX – The Sun? – Gain Spirit of the Night and +1.5 damage for the current level. Turns Isaac’s red hearts into bone hearts, but they revert once the effect ends. Also causes Curse of Darkness that cannot be dispelled.
Unlock method – Defeat Ultra Greedier as Tainted Jacob

XX – Judgement?

XX – Judgement? – Spawns a Restock Machine.
Unlock method – Defeat Ultra Greedier as Tainted Lazarus

XXI – The World?

XXI – The World? – Spawns a trap door to a crawl space.

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